Evolutionary Coupling Analysis
Predicted and experimental contacts
Secondary structure from ECs
EC score distribution and threshold
Top ECs
Rank |
Residue 1 |
Amino acid 1 |
Residue 2 |
Amino acid 2 |
EC score |
1 |
107 |
E |
117 |
H |
5.96 |
2 |
85 |
D |
101 |
H |
4.68 |
3 |
82 |
H |
101 |
H |
4.06 |
4 |
44 |
H |
56 |
H |
4.03 |
5 |
58 |
K |
85 |
D |
3.70 |
6 |
89 |
H |
101 |
H |
3.69 |
7 |
89 |
H |
97 |
V |
3.53 |
8 |
64 |
A |
81 |
K |
3.50 |
9 |
86 |
A |
102 |
A |
3.45 |
10 |
44 |
H |
52 |
Q |
3.42 |
11 |
54 |
L |
58 |
K |
3.13 |
12 |
107 |
E |
116 |
S |
2.97 |
13 |
57 |
A |
84 |
E |
2.92 |
14 |
37 |
H |
56 |
H |
2.84 |
15 |
40 |
E |
56 |
H |
2.78 |
16 |
89 |
H |
94 |
H |
2.73 |
17 |
99 |
T |
103 |
Q |
2.72 |
18 |
54 |
L |
89 |
H |
2.63 |
19 |
4 |
T |
13 |
V |
2.44 |
20 |
43 |
A |
47 |
E |
2.37 |
21 |
60 |
S |
64 |
A |
2.36 |
22 |
44 |
H |
49 |
H |
2.34 |
23 |
54 |
L |
85 |
D |
2.32 |
24 |
54 |
L |
92 |
E |
2.30 |
25 |
57 |
A |
88 |
K |
2.30 |
26 |
90 |
G |
98 |
A |
2.29 |
27 |
83 |
L |
87 |
I |
2.26 |
28 |
41 |
A |
57 |
A |
2.21 |
29 |
13 |
V |
36 |
K |
2.16 |
30 |
90 |
G |
102 |
A |
2.12 |
31 |
45 |
G |
88 |
K |
2.10 |
32 |
71 |
G |
101 |
H |
2.01 |
33 |
45 |
G |
53 |
L |
1.95 |
34 |
70 |
A |
82 |
H |
1.95 |
35 |
85 |
D |
89 |
H |
1.93 |
36 |
97 |
V |
101 |
H |
1.92 |
37 |
59 |
E |
63 |
H |
1.91 |
38 |
90 |
G |
95 |
V |
1.89 |
39 |
106 |
I |
117 |
H |
1.87 |
40 |
82 |
H |
104 |
E |
1.84 |
41 |
83 |
L |
105 |
A |
1.81 |
42 |
50 |
T |
88 |
K |
1.78 |
43 |
45 |
G |
50 |
T |
1.75 |
44 |
61 |
L |
82 |
H |
1.72 |
45 |
4 |
T |
12 |
S |
1.72 |
46 |
50 |
T |
91 |
E |
1.72 |
47 |
31 |
V |
36 |
K |
1.71 |
48 |
71 |
G |
83 |
L |
1.69 |
49 |
45 |
G |
57 |
A |
1.68 |
50 |
61 |
L |
85 |
D |
1.68 |
51 |
68 |
S |
81 |
K |
1.67 |
52 |
51 |
D |
92 |
E |
1.67 |
53 |
4 |
T |
11 |
A |
1.65 |
54 |
87 |
I |
102 |
A |
1.65 |
55 |
13 |
V |
33 |
E |
1.64 |
56 |
13 |
V |
34 |
A |
1.63 |
57 |
71 |
G |
82 |
H |
1.62 |
58 |
31 |
V |
35 |
V |
1.62 |
59 |
88 |
K |
92 |
E |
1.60 |
60 |
42 |
V |
84 |
E |
1.59 |
61 |
45 |
G |
91 |
E |
1.59 |
62 |
4 |
T |
9 |
I |
1.58 |
63 |
104 |
E |
116 |
S |
1.55 |
64 |
100 |
K |
116 |
S |
1.53 |
65 |
102 |
A |
116 |
S |
1.53 |
66 |
56 |
H |
60 |
S |
1.52 |
67 |
83 |
L |
102 |
A |
1.52 |
68 |
54 |
L |
88 |
K |
1.51 |
69 |
61 |
L |
71 |
G |
1.49 |
70 |
5 |
L |
9 |
I |
1.49 |
71 |
50 |
T |
95 |
V |
1.48 |
72 |
4 |
T |
10 |
A |
1.48 |
73 |
52 |
Q |
56 |
H |
1.48 |
74 |
87 |
I |
91 |
E |
1.47 |
75 |
11 |
A |
36 |
K |
1.46 |
76 |
13 |
V |
31 |
V |
1.45 |
77 |
38 |
A |
42 |
V |
1.43 |
78 |
60 |
S |
67 |
A |
1.42 |
79 |
12 |
S |
37 |
H |
1.39 |
80 |
5 |
L |
13 |
V |
1.37 |
81 |
71 |
G |
81 |
K |
1.37 |
82 |
106 |
I |
116 |
S |
1.35 |
83 |
37 |
H |
41 |
A |
1.34 |
84 |
60 |
S |
70 |
A |
1.34 |
85 |
101 |
H |
105 |
A |
1.33 |
86 |
105 |
A |
117 |
H |
1.31 |
87 |
4 |
T |
8 |
V |
1.31 |
88 |
100 |
K |
104 |
E |
1.31 |
89 |
9 |
I |
13 |
V |
1.31 |
90 |
46 |
K |
91 |
E |
1.30 |
91 |
61 |
L |
70 |
A |
1.30 |
92 |
33 |
E |
37 |
H |
1.29 |
93 |
6 |
I |
10 |
A |
1.29 |
94 |
55 |
E |
100 |
K |
1.29 |
95 |
5 |
L |
10 |
A |
1.29 |
96 |
61 |
L |
65 |
K |
1.24 |
97 |
43 |
A |
88 |
K |
1.24 |
98 |
48 |
G |
93 |
G |
1.23 |
99 |
51 |
D |
96 |
G |
1.22 |
100 |
40 |
E |
44 |
H |
1.22 |
101 |
84 |
E |
88 |
K |
1.18 |
102 |
105 |
A |
116 |
S |
1.18 |
103 |
65 |
K |
82 |
H |
1.18 |
104 |
60 |
S |
81 |
K |
1.18 |
105 |
12 |
S |
31 |
V |
1.17 |
106 |
8 |
V |
12 |
S |
1.17 |
Alignment robustness analysis
First most common residue correlation
Second most common residue correlation